ANTI-EXPRESSION LINE SOLUTION

Argireline® + SYN®-AKE Solution

Dual Neuro-Peptide Cosmetic Active

This advanced dual-peptide solution combines Argireline® (Acetyl Hexapeptide-8) and SYN®-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate), two widely studied cosmetic peptides commonly utilized in formulations targeting the appearance of expression lines and dynamic facial wrinkles.

Argireline® is frequently examined in cosmetic science for its interaction with pathways associated with muscle contraction signaling, while SYN®-AKE is a biomimetic peptide inspired by Waglerin-1 peptide sequences studied for their role in neuromuscular communication pathways.

Together, these peptides are often incorporated into formulations intended to improve the appearance of fine lines, particularly in areas subject to repetitive facial movement such as the forehead, eye contour region, and nasolabial folds.

This solution is supplied in a ready-to-use liquid format designed for incorporation into serums, emulsions, gels, and other cosmetic formulations.

Benefits

• Supports formulations targeting expression lines and dynamic wrinkles

• Frequently used in cosmetic formulations focused on smoothing skin appearance

• Compatible with a wide range of cosmetic bases

• Suitable for anti-aging and skin appearance research formulations

• Water-based and easy to incorporate

Recommended Use Level

1–10% in finished formulations

Appearance

Clear to slightly opalescent liquid

Solubility

Water soluble

Formulation Guidelines

• Add during cool-down phase below 40°C

• Compatible with most cosmetic emulsions, gels, and serums

• Avoid prolonged exposure to high heat

• Works well with hyaluronic acid, niacinamide, peptides, ectoine, and botanical extract.

INCI

Water (Aqua), Propanediol, Acetyl Hexapeptide-8, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Phenoxyethanol, Ethylhexylglycerin

Suggested Applications

• Anti-aging serums

• Eye creams

• Facial moisturizers

• Peptide gels

• Expression line targeted formulations